Publications

2023

  • Baldari CT, Onnis A, Andreano E, Del Giudice G, Rappuoli R (2023) Emerging roles of SARS-CoV-2 Spike/ACE2 in immune evasion and pathogenesis. Trends Immunol, https://doi.org/10.1016/j.it.2023.04.001.  Link
  • Capitani N, Cassioli C, Ravichandran K, Baldari CT (2023). Exploiting the RUSH system to study lytic granule biogenesis in CTLs. Methods Mol Biol. 2023; 2654: 421-436. doi: 10.1007/978-1-0716-3135-5_27 (The Immune Synapse: Methods and Protocols, Second Edition. ML Dustin & CT Baldari Eds.) Link
  • Chang HF, Schirra C, Pattu V, Krause E, Becherer U (2023) Lytic granule exocytosis at immune synapses: lessons from neuronal synapses. Front Immunol 14, doi: 10.3389/fimmu.2023.1177670
  • Cortacero K, McKenzie B, Müller S, Meyer N, Vergier B, Wilson DG, Luga H, Staufer S, Dustin ML, Valitutti S, Cussat-Blanc S (2023) Evolutionary design of explainable algorithms for biomedical image segmentation. Nat Commun 14, 7112. https://doi.org/10.1038/s41467-023-42664-x
  • Kvalvaag A, Valvo S, Céspedes PF, Saliba DG, Kurz E, Korobchevskaya K, Dustin ML (2023) Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse. PNAS 120 (6) e22113681; https://doi.org/10.1073/pnas.221136812, Link
  • Müller S, Filali L, Puissegur MP, Valitutti S (2023) Measuring CTL Lytic Granule Secretion and Target Cell Membrane Repair by Fluorescent Lipophilic Dye Uptake at the Lytic Synapse. Methods Mol Biol 2654: 463-476. doi: 10.1007/978-1-0716-3135-5_30, Link
  • Onnis A, Andreano E, Caccioli C, Finetti F, Della Bella C, Staufer O, Pantano E, Abbiento V, Marotta G, D’Elios MM, Rappuoli R, Baldari CT (2023). SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly. J Exp Med 220(2):e20220906. doi: 10.1084/jem.20220906, Link
  • Schirra C, Alawar N, Becherer U, Chang HF (2023) Separation of Single Core and Multicore Lytic Granules by Subcellular Fractionation and Immunoisolation. Methods Mol Biol. 2023;2654:159-167. doi: 10.1007/978-1-0716-3135-5_11, Link

2022

  • Capitani N, Onnis A, Finetti F, Cassioli C, Plebani A, Brunetti J, Troilo A, D’Elios S, Baronio M, Gazzurelli L, Della Bella C, Billadeau D, D’Elios MM, Lougaris V, Baldari CT (2022) A CVID-associated variant in the ciliogenesis protein CCDC28B disrupts immune synapse assembly. Cell Death Differ 29, 65-81. doi: 10.1038/s41418-021-00837-5. Link
  • Capitani N, Baldari CT (2022) The Immunological Synapse: An Emerging Target for Immune Evasion by Bacterial Pathogens. Front Immunol 13: 943344. doi: 10.3389/fimmu.2022.943344, Link
  • Cassioli C, Baldari CT (2022) The expanding arsenal of cytotoxic T cells. Front Immunol, 20 April 2022. doi: 10.3389/fimmu.2022.883010 (Review) Link
  • Cassioli C, Baldari CT (2022) Lymphocyte polarization during immune synapse assembly: centrosomal actin joins the game. Front Immunol 13, 830835. doi: 10.3389/fimmu.2022.830835 (Review) Link
  • Cassioli C, Patrussi L, Valitutti S, Baldari CT (2022) Learning from TCR signaling and immunological synapse assembly to build new Chimeric Antigen Receptors (CARs). Int J Mol Sci 23, 14255; https://doi.org/10.3390/ijms232214255, Link
  • Chang HF, Schirra C, Ninov M, Hahn U, Ravichandran K, Krause E, Becherer U, Bálint Š, Harkiolaki M, Urlaub H, Valitutti S, Baldari CT, Dustin ML, Jahn R, Rettig J. (2022) Identification of distinct cytotoxic gran-ules as the origin of supramolecular attack particles in T lymphocytes. Nat Commun 13, 1029. doi: 10.1038/s41467-022-28596-y. Link
  • Finetti F, Onnis A, Baldari CT (2022) IFT20: An Eclectic Regulator of Cellular Processes beyond Intraflagellar Transport. Int J Mol Sci 23: 12147. doi: 10.3390/ijms232012147, Link
  • Filali L, Puissegur MP, Cortacero K, Cussat-Blanc S, Khazen R, Van Acker N, Frenois, FX, Abreu A, Lamant L, Meyer N, Vergier B, Müller S, McKenzie B and Valitutti S (2022) Ultra-rapid lytic granule release from CTL activates Ca2+-dependent synaptic resistance pathways in melanoma cell. Science Advances. 8, eabk3234. doi: 10.1126/sciadv.abk3234. Link
  • McKenzie B, Khazen R and Valitutti S (2022) Greek fire, poison arrows, and scorpion bombs: how tumor cells defend against the siege weapons of cytotoxic T lymphocytes. Front Immunol, 3 May 2022. doi: doi.org/10.3389/fimmu.2022.894306 (Review) Link

2021

  • Cassioli C, Onnis A, Finetti F, Capitani N, Brunetti J, Compeer EB, Niederlova V, Stepanek O, Dustin ML, Baldari CT (2021) The Bardet-Biedl Syndrome complex component BBS1 controls T cell polarity during immune synapse assembly. J Cell Sci 134, jcs258462. doi: 10.1242/jcs.258462. Link
  • Cassioli C, Balint S, Compeer EB, Felce JH, Gamberucci A, Della Bella C, Felce SJ, Brunetti J, Valvo S, Pende D, D’Elios MM, Moretta L, Dustin ML, Baldari CT (2021) Increasing LFA-1 expression enhances immune synapse architecture and T cell receptor signaling in Jurkat E6.1 cells. Front Cell Dev Biol 9, 673446. doi: 10.3389/fcell.2021.673446. Link