Congratulations to the authors! The scientists involved in the study were able to identify a natural mechanism that could play a role in fighting cancer. (Picture of Dr. Hsin-Fang Chang und PD Dr. E Krause: © Hsin Fang Chang)
Li X, Schirra C, Wirkner ML, Tu SM, Lin CH, Hohmann M, Gu Y, Santiago L, Pardo J, Arretxe I, Alawar N, Chouaib A, Becherer U , Lee PH, Hsu HJ, Laschke MW, Baldari CT, Dustin ML, Rettig J, Krause E & Chang HF (2026) Lytic IFNγ is stored in cytotoxic granules and coreleased with granzyme B to mediate cytotoxic T lymphocyte killing. Cell Mol Immunol (2026). https://doi.org/10.1038/s41423-026-01391-1